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Dr. Tomoo Iwakuma Receives Over $2.7 Million NIH Grant to Study New Compound to Kill Cancer Cells Lacking p53 Gene

Dr. Iwakuma's study aims to find new ways and compounds to kill cancer cells that don’t have a normal p53 gene, which is found in about 50 percent of human cancers.

Addressing body image concerns in teen boys

While stereotypes may say differently, body image issues are not exclusive to girls; they are increasingly prevalent among teen boys as well, often leading to significant mental and physical health...

IBC Meeting Minutes

The Institutional Biosafety Committee (IBC) at Children’s Mercy Research Institute oversees research involving potentially hazardous biological agents as well as recombinant and synthetic nucleic acid...

Recognition

We strive to give our patients and families top-tier health care and a warm and welcoming experience. If you received excellent care or had a wonderful experience with one of our team members, we want to...

Let them play: Why play is the secret ingredient to your child's wellbeing

As parents, we often prioritize our children’s health, education and safety—but what if one of the most powerful tools for their development is something as simple as play? ...

22q11.2 ERAS: Discharge Recommendations

For children who had calcium values less than 8 mg/dL or ionized calcium less than 1.1 mmol/L following the procedure, continue the same dose of calcium and Calcitriol (if needed) at discharge.  Educate...

22q11.2 ERAS: Initial Calcium/Calcitriol Dose to Treat Hypocalcemia

Initial Dose Recommendations Calcitriol 0.025 mcg/kg/day PO/IV   in 2 divided doses  Calcium*  Neonates: Ca++ (elemental) 75 mg/kg/day PO   in 3 - 4 divided doses;   not to exceed...

22q11.2 ERAS: Typical Calcium/Calcitriol Stress Dosing

Start calcium/calcitriol stress does as planned with endocrinologist the day prior to procedure Stress Dose Recommendations Calcitriol 0.04 mcg/kg/day PO/IV   1 dose evening prior (max 1mcg/dose) ...

Nuances to Consider for Pelvic Exam

<!--[endif]-->Indication and intent <!-- [if !supportLists]-->In suspected pelvic inflammatory disease (PID), the goal is to assess for the presence of cervical motion tenderness, uterine/adnexal...

Alternative Regimen

If cephalosporin allergy or history of penicillin anaphylaxis: Inpatient Clindamycin 13 mg/kg (max 900 mg) IV q 8 hrs - and - Gentamicin  Preferred: 3 ‐ 5 mg/kg IV daily - or - Alternative: 2 mg/kg IV...

Dosing Options

Inpatient Metronidazole < 45 kg: 10 - 13 mg/kg (max 500 mg/dose) PO or IV q 8 hrs Inpatient, transition to oral therapies Metronidazole < 45 kg: 10 - 13 mg/kg (max 500 mg/dose) PO q 8 hrs Outpatient...

PCR by First Catch Urine

No void during the previous hour No genital cleaning 20 - 30 mL sample: do not overfill DO NOT order as an add-on unless an appropriate sample is confirmed by the lab These pathways do not establish a...

Summer break guide: Boosting your kids' and teens' mental health

Summer break is a time of excitement and relaxation for many kids and teens, but it can also bring unique challenges to their mental health. Without the structure and routine of school, young people may...

Vaccine Update: The Impact of Vaccine Hesitancy and Strategies for Mitigation

Column Author: Christine A. Symes, MSN, APRN, CPNP Column Editor: Angela L. Myers, MD, MPH | Chief Wellbeing Officer Vaccine hesitancy (VH) in pediatrics is complicated and requires a...

What’s the Diagnosis?: Dermatology

Column Author and Editor: Sean Reynolds, MBBCH | Associate Program Director, Pediatric Dermatology Fellowship A 3-week-old infant presents to the dermatology clinic for evaluation of a rash.

Myocarditis: Cartier’s Story

Cartier had a severe form of myocarditis, inflammation of the heart muscle. Through the support of his family and a large multidisciplinary care team, he made a full recovery — no transplant needed!

Goals of Therapy

  Goals of therapy should be individualized based on clinical picture including underlying etiology and patient response to interventions Midazolam Pentobarbital Ketamine Seizure control (note goal...

Kulesa Lab Applies New Technology to Research Childhood Cancer and Other Diseases

Dr. Paul Kulesa's research focuses on neural crest cell development in the embryo and how these cells migrate long distances and differentiate into specific cell types (bone, cartilage and neurons).

Measles Testing Guidance for Patients Seen Outside of Children's Mercy

PCR testing has the highest yield in the first 3 days from the onset of rash and decreases over time. The yield of IgM testing increases 3 or more days after the onset of the rash. Obtain all laboratory...

Animal Bites (Mammal): Post-Exposure Prophylaxis Vaccine and Immunoglobulin Recommendations

Pathogen Source of Bite Recommendations Post-Exposure Prophylaxis Dosing and Administration Rabiesa   Dogs, cats, and ferrets Healthy domestic pets without initial signs of rabies (regardless of...