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Neonatal Diseases: A study on genetic risk factors
More and more often, doctors and researchers are understanding that there may be a genetic reason why some infants have a greater risk of becoming sick from certain diseases. Some of these diseases are directly or indirectly caused by germs, including bacteria, viruses or fungi...
More and more often, doctors and researchers are understanding that there may be a genetic reason why some infants have a greater risk of becoming sick from certain diseases. Some of these diseases are directly or indirectly caused by germs, including bacteria, viruses or fungi. If we can identify the genetic links that make some infants more likely to become sick from these germs, we may be able to target treatment to these higher-risk babies in the future, which could prevent severe illness and even death. The study team is looking for genetic differences that might make certain babies more likely to become sick from Necrotizing Enterocolitis (NEC), Bronchopulmonary Dysplasia (BPD) and specific blood infections (Group B Strep and Herpes Simplex) during the birth to 12-month-old period.
Pre-term NICU infants: A study of the inhaled drug ciclesonide (i.e.,Alvesco) in babies at risk of BPD
This study is for: -Babies day of life 8-35 -Born between 23-25 weeks on invasive mechanical ventilation -Currently in the Neonatal Intensive Care Unit (NICU)...
This study is for: -Babies day of life 8-35 -Born between 23-25 weeks on invasive mechanical ventilation -Currently in the Neonatal Intensive Care Unit (NICU) This study is being done to test if ciclesonide will be useful to prevent BPD (a chronic lung disease) in premature infants without the major side-effects of other steroids. We want to better understand how inhaled ciclesonide is tolerated in premature infants. Eligible participants who meet inclusion/exclusion screening criteria could be approached by a study team member.